Quinine is an alkaloid which exists in the cinchona bark, and which is extracted by a chemical proc PDF Print E-mail
Sunday, 02 July 2006
Ayurvedic remedies for Typhoid that the bihydro-ohlorides of quinine, quinidine, cinchonidine and cinchonine when injected in the usual strengths into the muscles of rabbits cause oedema, irritation and necrosis of the



tissues. Contrary to the usual belief, there was little difference in the action of cinchonine as compared with quinine. They go so far as to say that the injection of these alkaloidal salts into the muscles of man should be considered as malpraxis, and that "there is only one method of administering the cinchona alkaloids and that is by the mouth". "Very rarely in grave cases, quinine base should be injected intravenously". Rut the editor of Practical Medicine" says that) this method should be reserved for cases in which there are good and sufficient reasons, such as persistent vomiting or failure to absorb the drugs. The proportion of cases in which serious consequences follow in practice from intramuscular injections is small; and that the method may be reserved for those cases in which there is a real necessity for the procedure.
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